Structure of a stacked anthraquinone–DNA complex

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Structure of a stacked anthraquinone-DNA complex.

The crystal structure of the telomeric sequence d(UBrAGG) interacting with an anthraquinone derivative has been solved by MAD. In all previously studied complexes of intercalating drugs, the drug is usually sandwiched between two DNA base pairs. Instead, the present structure looks like a crystal of stacked anthraquinone molecules in which isolated base pairs are intercalated. Unusual base pair...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section F Structural Biology and Crystallization Communications

سال: 2010

ISSN: 1744-3091

DOI: 10.1107/s1744309110030034